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An Easier Option?

A common practice in other countries, radiofrequency ablation (RFA) is now available in the United States. Developed over fifteen years ago, this non-surgical alternative shrinks the nodules usually without compromising thyroid function and helps avoid the long recovery times of thyroid surgery.

Radiofrequency ablation of the thyroid was popularized by Professor Baek in South Korea and has since been continuously adopted by many medical practitioners.

Worldwide, approximately seven thousand procedures are performed each year in just a few facilities.

What to Expect During the Procedure

You will be able to breathe, swallow and talk normally the entire time. Two grounding pads will be attached to your thigh. Your neck will be cleaned and head will be placed on a small cushion with your neck extended. The doctor will give you pain medication in the area of the thyroid.

The doctor will ask you several times during the treatment how you are doing and whether you feel pain, and can easily give you more if you are uncomfortable at any time.

Preparing For Radiofrequency Ablation

Radio-frequency ablation takes place in an outpatient setting. Although you will not be under general anesthesia, you will need to follow some pre-procedural instructions from your healthcare facility. They will review the list of your current medications and provide instructions.

In most cases, your medications will not affect the procedure. If you take medication for diabetes or high blood pressure, you will most likely be instructed to keep taking it. If you’re on blood thinning medication, you will probably need to stop taking it for a few days prior to the procedure. Be sure to inform your physician if you have a pacemaker, implants, are pregnant, or on any medication (especially for blood thinning). Don’t wear makeup, lipstick, or any metal jewelry on the day of the procedure.

Advantages of Radiofrequency Ablation of Thyroid Nodules

Compared with surgery, the primary advantages of radiofrequency ablation are:

  • The potential for fewer complications
  • Generally shorter recovery time with a quick return to normal activities
  • Increased likelihood of preservation of thyroid function.

The entire procedure takes between fifteen minutes to one hour. Because it is minimally invasive and does not require general anesthesia, you avoid the external scarring of traditional thyroid surgery, and the associated risks of anesthesia. Radio-frequency ablation may also minimize the risk of permanent damage to the vocal cord nerve or to the parathyroid glands.

One of the most meaningful long-term advantages is that you may not need to take lifelong thyroid medication. The treatment preserves healthy thyroid tissue, which allows the thyroid to continue functioning normally — no ongoing medication management, with the difficulties of achieving the correct thyroid hormone dosage.

Radio-frequency ablation is highly effective for benign thyroid nodules. Depending on the type (solid vs. fluid filled vs. a combination of the two), nodules shrink anywhere between 60-90% after one year, with approximately 80% on average

How Effective Is This Procedure?

Clinical trials have measured the rate of reduction, therapeutic success, changes in symptoms and cosmetic improvement of benign thyroid nodules.

For “cold” benign nodules (those that do not produce excess thyroid hormone), clinical trials have shown a mean reduction rate of 32.7 to 58.2% at one month, and 50.7 to 84.8% at six months. In most patients, nodule related symptoms and cosmetic problems also significantly improved or disappeared. In a long term follow-up study, radio-frequency ablation was effective over a four year period with the nodules consistently decreasing by 93.5%.

For “hot” benign thyroid nodules (those that do produce excess thyroid hormone), clinical trial have shown volume reduction rates of 52.6 to 70.7% at six months, and improved or normalized thyroid function in most patients. In a multi-center study, hyperthyroidism caused by “hot” nodules improved in all patients and was completely normalized in 81.8% of patients. This led to the conclusion that radio-frequency ablation can be considered as an alternative to thyroid surgery or radioactive iodine therapy.

How It Works

A generator creates an electric circuit. The electrode is designed to optimally deliver energy to the area that is being treated. During the procedure, the doctor will place the tip of the probe into the thyroid nodule. The generator creates a high frequency wave and sends it directly to the end of the probe. Your doctor can then adjust the area being treated as needed to ensure that you achieve the desired results.

You will often hear background noise and “crackling” sounds throughout the procedure. These sounds are normal and signify an appropriate response is taking place.

How Long Does the Procedure Last?

While the procedure itself takes less than an hour, the entire process may take 2-3 hours. Pre-procedural care and post procedural monitoring takes an additional hour. When the procedure is complete, a small bandage will be placed on the treatment site and the neck may be cooled with ice packs.

What Happens to the Nodules After Treatment?

In the weeks following the procedure, the cells of the treated thyroid nodule are removed by the body’s immune system. Most patients notice the nodule has already become smaller in just two to three weeks, with solid nodules taking longer than cystic nodules.

Part or all of targeted thyroid nodules may be permanently destroyed during the procedure.
Immune cells of the body then break down the affected areas, which shrinks the nodules. The percent reduction depends on the original size and nature of the nodules, with around 40–60% after three months and about 60–90% after one year. In the years after the procedure, all that remains in the treated area is scar tissue. While some of the nodule around this scar may remain, it is generally smaller than the same nodule before treatment. The surrounding healthy thyroid gland remains unharmed and can continue to produce thyroid hormone. It is highly unlikely that thyroid hormone will be required after treatment.

Often, difficulty swallowing, feelings of pressure or tightness of the throat, or even the bulky appearance of the nodule is usually significantly decreased or no longer detectable.

How Many Treatments Are Necessary?

For most nodules less than 4 cm, one treatment will sufficiently decrease the size of the nodules and improve symptoms. When nodules are close to vocal cord nerves, or with very large nodules, repeated procedures may be necessary. Untreated areas of “hot” nodules may interfere with the improvement in thyroid function. In these instances, complete ablation may be required. For this reason, more than one treatment session may be necessary to successfully treat “hot” nodules.

Are There Any Side Effects or Complications?

In a multi-center study of 1459 patients organized by the Korean Society of Thyroid Radiology, the overall complication rate following radiofrequency ablation was 3.3%. The major complication rate was 1.4%. While uncommon, complications can be:
• Temporary voice changes, such as hoarseness.
• Slight bleeding — usually disappears on its own within one day, or at the most, up to three months.
• Wound infections
• In rare cases, vomiting, coughing, or seared skin at the treatment site may occur

• Patients with AFTN (“hot” thyroid nodules) have the possibility of hypothyroidism after the procedure. Although rare, a complication may require an inpatient hospital stay or follow-up treatment.

Is There Any Follow-Up Care?

Following radio-frequency ablation, your physician may monitor the treated nodules with ultrasound scans or lab tests.

Is This Procedure Reimbursed By Insurance?

Although this procedure is FDA cleared, at this moment in time it is a cash based procedure.

The cost will be provided by your provider and/or institution.However, as a patient you have the right to submit to insurance for reimbursement after the procedure has been completed. Your physician’s office can help guide you in this process.

Leading Edge Option for Benign Thyroid Nodules

In the final analysis, radiofrequency ablation (RFA) is an exciting alternative for patients who experience problems from benign thyroid nodules— offering the potential for less pain, less downtime and less external scarring than with surgery and without the risks of RAI. It is a safe and validated procedure that is now approved in the United States.

With its long lasting effects, radiofrequency ablation is a breakthrough in treating the symptoms of thyroid nodules.
Ultimately, your physician can help determine the most effective treatment option for you.

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